Use of Aripiprazole in Clozapine Induced Enuresis: Report of Two Cases
Journal of Korean Medical Science
;
: 333-335, 2010.
Article
in English
| WPRIM
| ID: wpr-207476
ABSTRACT
This report describes the efficacy of combined use of aripiprazole in the treatment of a patient with clozapine induced enuresis. Aripiprazole acts as a potential dopamine partial agonist and the dopamine blockade in the basal ganglia might be one of the causes of urinary incontinence and enuresis. We speculate that aripiprazole functioned as a D2 agonist in hypodopaminergic state of basal ganglia caused by clozapine and maintained dopamine level that would improve enuresis ultimately.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Piperazines
/
Schizophrenia, Paranoid
/
Antipsychotic Agents
/
Dopamine
/
Clozapine
/
Quinolones
/
Dopamine Agonists
/
Drug Therapy, Combination
/
Enuresis
Limits:
Adult
/
Humans
/
Male
Language:
English
Journal:
Journal of Korean Medical Science
Year:
2010
Type:
Article
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