Quantitation of Sunburn Cell Production in Mouse Skin by Ultarviolet Irradiation / 대한피부과학회지
Korean Journal of Dermatology
;
: 8-15, 1986.
Article
in Korean
| WPRIM
| ID: wpr-208616
ABSTRACT
In this study, a total of 115 ICR male albino haired mice were used and divided into two groups(A & B) for experiment. In group A(65 mice), quantiatation of sunburn cell(SBC) production and its distribution according to the time course after ultraviolet irradiation was measured. In group B(50mice), quantitation of dose-response experiments for SBC production after ultraviolet irradiation was measured. The results were as follows ]. SBCs were recognized by 2 hours after irradiation. There was a tendency to increase from 2 hours to 24 hours and decrease from then to l week after irradiation, 2. The increase of SBCs in lower epidermis 2 hours io 8 hours after exposure and in upper epidermis 24 hours after irradiation were statistically significant (p<0. 05). SBG number in all layers declined from 36 hours to 1 week after exposure. 3. The linear relationship which observed(y=8.09+0.85x, R=0.87) suggests a dose-response relationship between UVB dose and SBC number.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Skin
/
Sunburn
/
Epidermis
/
Hair
Limits:
Animals
/
Humans
/
Male
Language:
Korean
Journal:
Korean Journal of Dermatology
Year:
1986
Type:
Article
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