A case of secondary amyloidosis presenting acute renal failure in rheumatoid arthritis patient / 대한내과학회지

ABSTRACT

Amyloidosis is a heterogenous group of often fatal disorders characterized by extracellular deposition of a proteinaceous material with a unique fibrillar form in various tissues and organs. Deposition of amyloid may cause widespread dysfunction of the involved organs. A secondary amyloidosis is AA amyloidosis and rheumatoid arthritis is one of the main underlying disease. We report a case of secondary amyloidosis in a 52 year old woman with rheumatoid arthritis. She had suffered from rheumatoid arthritis for 17 years and her hands and feet were deformed. She was presented with oliguric acute renal failure. She was confirmed by showing apple green birefringence under the polarized microscope with Congo-red stain through renal and rectal biopsy. We couldn't find any previous report of the secondary amyloidosis among the patients presenting oliguric acute renal failure without proteinuria in the Korean literatures.