The Effect of Stress on Gastrointestinal Physiology in Irritable Bowel Syndrome / 대한내과학회지
Korean Journal of Medicine
;
: 164-169, 2012.
Article
in Korean
| WPRIM
| ID: wpr-208726
ABSTRACT
Stress is an acute threat to the homeostasis of an organism by events in the outside world and evokes adaptive responses to preserve the stability of the internal environment. This adaptation can be carried out by means of alterations in HPA axis hormones, the autonomic nervous system, metabolic and immune systems. However, chronic stress can lead to changes in adaptation system and cause a functional disease such as irritable bowel syndrome (IBS). In fact, stress plays an important role in the development and exacerbations of IBS symptoms and it has been postulated that stress have an effect on the pathophysiology of IBS, including an increase in visceral perception, alterations in gastrointestinal motility and increased intestinal permeability. Therefore, Therapeutic approaches targeting stress management could be of great benefit for patients with irritable bowel syndrome.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Permeability
/
Autonomic Nervous System
/
Axis, Cervical Vertebra
/
Irritable Bowel Syndrome
/
Gastrointestinal Motility
/
Homeostasis
/
Hypersensitivity
/
Immune System
Limits:
Humans
Language:
Korean
Journal:
Korean Journal of Medicine
Year:
2012
Type:
Article
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