Molecular Targeted Therapy in Modern Oncology: Imaging Assessment of Treatment Response and Toxicities

Katherine-M KRAJEWSKI; Marta BRASCHI-AMIRFARZAN; Pamela-J DIPIRO; Jyothi-P JAGANNATHAN; Atul-B SHINAGARE

Katherine-M KRAJEWSKI; Marta BRASCHI-AMIRFARZAN; Pamela-J DIPIRO; Jyothi-P JAGANNATHAN; Atul-B SHINAGARE.

Korean Journal of Radiology ; : 28-41, 2017.

Article in English | WPRIM | ID: wpr-208837

ABSTRACT

ABSTRACT

Oncology is a rapidly evolving field with a shift toward personalized cancer treatment. The use of therapies targeted to the molecular features of individual tumors and the tumor microenvironment has become much more common. In this review, anti-angiogenic and other molecular targeted therapies are discussed, with a focus on typical and atypical response patterns and imaging manifestations of drug toxicities.

Subject(s)

Humans; Drug-Related Side Effects and Adverse Reactions; Molecular Targeted Therapy; ErbB Receptors; Response Evaluation Criteria in Solid Tumors; Tumor Microenvironment; Vascular Endothelial Growth Factor A

Vascular endothelial growth factor; Response Evaluation Criteria in Solid Tumors; Epidermal growth factor receptor; Anaplastic lymphoma kinase; Mammalian target of rapamycin; Human epidermal growth factor receptor 2

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Vascular Endothelial Growth Factor A / Drug-Related Side Effects and Adverse Reactions / Molecular Targeted Therapy / Tumor Microenvironment / ErbB Receptors / Response Evaluation Criteria in Solid Tumors Limits: Humans Language: English Journal: Korean Journal of Radiology Year: 2017 Type: Article

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