A Case of Propylthiouracil induced Antineutrophil Cytoplasmic Antibody Positive Pyoderma Gangrenosum
Journal of Rheumatic Diseases
;
: 162-165, 2014.
Article
in Korean
| WPRIM
| ID: wpr-20888
ABSTRACT
Pyoderma gangrenosum (PG) is a rare disease that causes chronic skin ulcers, and it has recently been known to be related to changes in the immune system such as dysfunction of neutrophils. Over 50% of patients with PG have an underlying systemic disease, and rarely are there various medicines causing the disease, including iodide, bromide, and isotretinoin. A 49-year-old man had recurrent skin ulcers in his lower extremities. He had a history of taking propylthiouracil (PTU) for 10 years as a treatment for Graves' disease. Here, we describe a case of PTU-induced ANCA positive PG in a patient with hyperthyroidism, who has been improved after the cessation of PTU.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Propylthiouracil
/
Skin Ulcer
/
Isotretinoin
/
Graves Disease
/
Pyoderma Gangrenosum
/
Antibodies, Antineutrophil Cytoplasmic
/
Lower Extremity
/
Rare Diseases
/
Hyperthyroidism
/
Immune System
Limits:
Humans
Language:
Korean
Journal:
Journal of Rheumatic Diseases
Year:
2014
Type:
Article
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