Refractory Duodenal Crohn's Disease Successfully Treated with Infliximab
Intestinal Research
;
: 66-69, 2014.
Article
in English
| WPRIM
| ID: wpr-208946
ABSTRACT
Crohn's disease (CD) may involve any part of the gastrointestinal tract, from the mouth to the anus. Approximately >90% of cases occur in the small bowel and colon. Upper gastrointestinal involvement, especially duodenal manifestation, is relatively rare. Therefore, adequate medical treatment for duodenal CD has not yet been established. We report a case of CD with duodenal involvement. A 46-year-old man with Crohn's ileocolitis presented to our hospital with right upper quadrant pain. An endoscopy showed a deep excavated ulcer with deformity at the duodenal bulb, and he was initially treated with azathioprine (1 mg/kg), Pentasa (3.0 g/day), and a proton pump inhibitor for 1 year. However, the deep ulcer did not heal. Therefore, infliximab infusion therapy was initiated, and the duodenal lesion completely resolved on follow-up esophagogastroduodenoscopy. We report a case of duodenal CD that completely resolved following infliximab infusion, with a review of the literature.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Anal Canal
/
Azathioprine
/
Congenital Abnormalities
/
Ulcer
/
Crohn Disease
/
Follow-Up Studies
/
Endoscopy, Digestive System
/
Proton Pumps
/
Colon
/
Mesalamine
Type of study:
Observational study
/
Prognostic study
Limits:
Humans
Language:
English
Journal:
Intestinal Research
Year:
2014
Type:
Article
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