Treatment Outcomes and Quality of Life in Oropharyngeal Cancer after Surgery-based versus Radiation-based Treatment
Clinical and Experimental Otorhinolaryngology
;
: 153-160, 2010.
Article
in English
| WPRIM
| ID: wpr-209020
ABSTRACT
OBJECTIVES:
Advances in reconstruction and conservative surgery and the importance of quality of life (QOL) encouraged this reevaluation of surgery-based treatments for oropharyngeal cancer. We tried to compare treatment outcome and QOL after surgery-based versus radiation-based treatment in oropharyngeal cancer.METHODS:
The 133 eligible patients were divided into surgery-based and radiotherapy (RT)-based treatment groups. Medical records were reviewed, and EORTC QLQ-C30 and HN65 questionnaires were completed for survivors. Three-year overall survivals, disease-free survivals, locoregional control rates, and QOL scores were compared between the two groups.RESULTS:
Demographic data and overall stages were not significantly different between the two groups, and all survival rates were non-significantly different, either. The scores for most QOL items were equivalent, however, for a few items, scores were significantly better in surgery-based group.CONCLUSION:
The surgery-based group achieved equivalent treatment outcomes and slightly better QOL scores than the RT-based group. The results of this study suggest that surgery could still be considered as a first-line therapy for oropharyngeal cancer.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Quality of Life
/
Oropharyngeal Neoplasms
/
Medical Records
/
Survival Rate
/
Surveys and Questionnaires
/
Treatment Outcome
/
Survivors
/
Disease-Free Survival
Limits:
Humans
Language:
English
Journal:
Clinical and Experimental Otorhinolaryngology
Year:
2010
Type:
Article
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