The Clinical Results of Hemodilution Therapy for Retinal Vein Obstructive Disease

ABSTRACT

PURPOSE: To evaluate the clinical results of isovolemic hemodilution for central retinal vein occlusion and branch retinal vein occlusion patients. METHODS: We have done phlebotomy and then infused same volume of hydroxyethyl starch to 6 CRVO and 5 BRVO patients, and control group(5 CRVO, 9 BRVO) was observed. We have checked hematocrit the next day. If the hematocrit was reached to final target, we stopped the hemodilution therapy. Anterior segment examination, visual acuity, fundus photography, fluorescein angiography, laboratory test was done. and compare the preoperative value to postoperative result. RESULTS: The final visual acuity improved in 10 eyes undergoing isovolemic hemodilution and control group 12 eyes. In fluorescein angiography, Arm to retina time is about 19.03+/-10.86%, venous filling time is 14.80+/-8.57%. The average reduction of hemoglobin is 22.12+/-4.33%, hematocrit is 22.74+/-4.71%. In laboratroy test, platelet, triglyceride, phospholipid, CSR, HDL is reduced. CONCLUSIONS: The retinal blood flow was improved by hemodilution in CRVO and BRVO patients. But further investigation and long-term follow up result was needed in this study.