Clinical Study of Ocular Adnexal Extranodal Marginal Zone B-cell Lymphoma: From the Perspective of Dermatology / 대한피부과학회지
Korean Journal of Dermatology
;
: 403-412, 2012.
Article
in Korean
| WPRIM
| ID: wpr-20988
ABSTRACT
BACKGROUND:
The ocular adnexal extranodal marginal zone B-cell lymphoma has been known as the 2nd most common extranodal marginal zone B-cell lymphoma, which presents as the dermatologic symptom and sign, such as orbital mass and swelling. However, the ocular adnexal extranodal marginal zone B-cell lymphoma has been few reported in the dermatologic literature.OBJECTIVE:
We described the clinical and histopathological features of ocular adnexal extranodal marginal zone B-cell lymphoma from the perspective of dermatology.METHODS:
Ninety-nine cases of ocular adnexal extranodal marginal zone B-cell lymphoma patients were included in this study, among the 352 patients, who were diagnosed with extranodal marginal zone B-cell lymphoma between March 1998 and February 2011. Their medical records and histopathologic slides were retrospectively reviewed.RESULTS:
Among the 352 patient of extranodal marginal zone B-cell lymphoma, ocular adnexal extranodal marginal zone B-cell lymphoma occurred in 99 patients (28.1%). The ratio between male and female was 12, and the mean age was 50 years (range; 20~54 years). Ocular adnexal extranodal marginal zone B-cell lymphoma presented as orbital mass (39.1%), conjunctival injection (25.6%), orbital swelling (19.5%), and etc. In most patients, lesions were located in conjunctiva (63.8%) or orbit (14.5%). 76.7% of patients presented with Ann Arbor stage I disease. Relapses occurred in 8.4% of patients during the follow-up period.CONCLUSION:
When dermatologists meet patients presenting with orbital mass and swelling, dermatologists consider the possibility of ocular adnexal extranodal marginal zone B-cell lymphoma and consultation with the ophthalmologists.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Orbit
/
Recurrence
/
B-Lymphocytes
/
Medical Records
/
Retrospective Studies
/
Follow-Up Studies
/
Lymphoma, B-Cell, Marginal Zone
/
Conjunctiva
/
Dermatology
Type of study:
Observational study
/
Prognostic study
/
Risk factors
Limits:
Female
/
Humans
/
Male
Language:
Korean
Journal:
Korean Journal of Dermatology
Year:
2012
Type:
Article
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