Evaluation of the Behavior of Spinal Deformities in Tuberculosis of the Spine in Adults
Asian Spine Journal
;
: 741-747, 2015.
Article
in English
| WPRIM
| ID: wpr-209953
ABSTRACT
STUDY DESIGN:
A prospective clinical study.PURPOSE:
The objective of the present study was to evaluate the behavior of spinal deformities in tuberculosis (TB) of the spine during the initial 2 years and to suggest remedial measures. OVERVIEW OF LITERATURE Spinal TB is the most common cause of a kyphotic deformity in many parts of the world. Treatment of the established deformity is difficult, hazardous and has a high complication rate.METHODS:
We followed 50 adult patients treated for spinal TB for a minimum of 2 years. Average values of vertebral body height loss (VBL), deformity angle, kyphosis angle, and lumbosacral joint angle at the final follow-up were compared with the values at initial presentation. The relationship between the amount of initial VBL and final kyphotic angle was analyzed.RESULTS:
Average values of VBL, deformity angle, kyphosis angle, and lumbosacral joint angle at initial presentation were 0.26, 12.51degrees, 2.26degrees, and 12.3degrees, respectively; and the corresponding values at the final follow-up were 0.7, 17.8degrees, 5.64degrees, and 10.8degrees, respectively. The increase was extremely significant for the deformity angle (initial vs. 6th month, p=0.000; 6th month vs. 24th month, p=0.000) and kyphotic angle (initial vs. 6th month, p=0.003; 6th month vs. 24th month, p=0.000) in the thoracic and thoracolumbar regions during the first 2 years of the disease process. The increase in the deformity angle in the lumbar region was significant only in the initial 6 months (p=0.01). We could not find any correlation between the initial VBL and the final kyphotic angle (r=0.302, p>0.05).CONCLUSIONS:
Different regions of the vertebral column respond differently to bony destruction caused by spinal TB. Deformity progression is more significant during the initial 6 months of the disease process, and this may be the best time to take remedial measures to prevent development/progression of the deformity. Kyphotic deformity keeps increasing even after 6 months of antituberculous treatment, and it does not correlate with the initial VBL in adults.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Spine
/
Congenital Abnormalities
/
Tuberculosis
/
Tuberculosis, Spinal
/
Body Height
/
Prospective Studies
/
Follow-Up Studies
/
Joints
/
Kyphosis
/
Lumbosacral Region
Type of study:
Observational study
/
Prognostic study
Limits:
Adult
/
Humans
Language:
English
Journal:
Asian Spine Journal
Year:
2015
Type:
Article
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