The Clinical Characteristics of Optic Neuritis in Korean Children
Korean Journal of Ophthalmology
;
: 116-120, 2011.
Article
in English
| WPRIM
| ID: wpr-210237
ABSTRACT
PURPOSE:
To study the clinical characteristics of optic neuritis in Korean children.METHODS:
A retrospective review of the medical charts of 20 patients who were diagnosed with optic neuritis before age 10 was conducted in this study. Data were collected on the demographics, clinical features, use of intravenous corticosteroids, neuroimaging, and diagnosis of multiple sclerosis.RESULTS:
The mean age at diagnosis was 6.5 +/- 1.8 years (range, 3 to 9 years). Seventeen patients (85%) were female, and 13 patients (65%) exhibited bilateral diseases. Visual acuity had decreased to or =20 / 40 in 16 of the 20 patients. The mean duration between the worst visual acuity and 20 / 40 was 2.30 +/- 2.91 months. Intravenous corticosteroid treatment was performed in 15 patients and exerted a beneficial effect on the visual outcomes. Disc swelling was observed in 75.8% of the affected eyes. Multiple sclerosis was diagnosed in five patients with a mean follow-up period of 21.9 +/- 20.3 months. The presence of lesions in brain magnetic resonance images was identified as the most significant factor with regards to the occurrence of multiple sclerosis.CONCLUSIONS:
In children with optic neuritis, a profound decrease in initial visual acuity and rapid recovery of visual acuity were confirmed. Corticosteroid treatment resulted in a beneficial effect on visual outcomes, but had no effect on the risk of multiple sclerosis.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Severity of Illness Index
/
Magnetic Resonance Imaging
/
Visual Acuity
/
Optic Neuritis
/
Incidence
/
Retrospective Studies
/
Age Distribution
/
Republic of Korea
Type of study:
Incidence study
/
Observational study
/
Prognostic study
Limits:
Child
/
Child, preschool
/
Female
/
Humans
/
Male
Country/Region as subject:
Asia
Language:
English
Journal:
Korean Journal of Ophthalmology
Year:
2011
Type:
Article
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