A Comparison of Epidural Morphine-Bupivacaine with Intravenous Morphine-Ketorolac in Patient-Controlled Analgesia after Gynecologic Operation / 대한마취과학회지
Korean Journal of Anesthesiology
;
: 560-564, 2004.
Article
in Korean
| WPRIM
| ID: wpr-210351
ABSTRACT
BACKGROUND:
Postoperative pain control is provided for humanitarian reasons and to alleviate nociception-induced responses, such as endocrine metabolic responses, autonomic reflexes, which have adverse effects on organ function, and other undesirable results. Of the various methods of treatment, patient-controlled analgesia (PCA) is considered the gold standard for the of control postoperative pain. PCA can be administered via intraveous, epidural, or subcutaneous routes. Although patient-controlled epidural analgesia (PCEA) has been compared to IV-PCA, there is no optimal administrative route for the treatment of postoperative pain. This randomized study compared the effectiveness of PCEA and IV-PCA on postoperative pain and the side-effects after gynecologic surgery.METHODS:
Ninety-seven patients undergoing gynecologic surgery were randomly assigned to receive either IV-PCA using a mixture of morphine and ketorolac or PCEA using 0.1% bupivacaine and morphine. Pain intensity was tested using a visual analog scale (VAS) until postoperative day 2. Nausea, vomiting, sedation, and pruritus were also measured.RESULTS:
Among the 97 patients, 12 patients were excluded during study. Pain relief was better at rest and after coughing in the PCEA group during the 2 postoperative days, except at the first visit. Additional analgesics were used significantly less in the PCEA group, whilst the incidence of other complications was comparable in the IV-PCA and PCEA groups.CONCLUSIONS:
After gynecologic surgery, PCEA using bupivacaine and morphine provides better pain relief than IV-PCA using morphine and ketorolac.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pain, Postoperative
/
Pruritus
/
Reflex
/
Gynecologic Surgical Procedures
/
Vomiting
/
Bupivacaine
/
Passive Cutaneous Anaphylaxis
/
Analgesia, Epidural
/
Incidence
/
Analgesia, Patient-Controlled
Type of study:
Controlled clinical trial
/
Incidence study
/
Prognostic study
Limits:
Female
/
Humans
Language:
Korean
Journal:
Korean Journal of Anesthesiology
Year:
2004
Type:
Article
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