A Case of Muir-Torre Syndrome: Extra-ocular Sebaceous Carcinoma in a Patient with Breast Cancer / 대한피부과학회지
Korean Journal of Dermatology
;
: 696-699, 2010.
Article
in Korean
| WPRIM
| ID: wpr-210546
ABSTRACT
Muir-Torre syndrome is defined by concurrent or sequential development of internal malignancy - most commonly colorectal cancer - and sebaceous neoplasm or multiple keratoacanthomas. Recent studies revealed it was caused by mutations in DNA mismatch repair genes, and suggested screening for mismatch repair gene defects may be of value for patients with Muir-Torre syndrome. We, herein, report a patient with Muir-Torre syndrome, who developed breast cancer and extra-ocular sebaceous carcinoma. In addition, we discussed our experience of immunohistochemical staining for mismatch repair protein with a review of the literature.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Breast
/
Breast Neoplasms
/
Colorectal Neoplasms
/
Mass Screening
/
DNA Mismatch Repair
/
Muir-Torre Syndrome
/
Keratoacanthoma
Type of study:
Screening study
Limits:
Humans
Language:
Korean
Journal:
Korean Journal of Dermatology
Year:
2010
Type:
Article
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