Understanding the Rome IV: Esophageal Disorders / 대한내과학회지
Korean Journal of Medicine
;
: 354-361, 2017.
Article
in Korean
| WPRIM
| ID: wpr-211172
ABSTRACT
The Rome IV criteria, published in 2016, encompass upper gastrointestinal lesions of functional esophageal disorders and functional gastroduodenal disorders. Functional esophageal disorders include functional chest pain, functional heartburn, reflux hypersensitivity, globus, and functional dysphagia. Patients with functional esophageal disorders typically have esophageal symptoms that are not associated with structural, inflammatory, or major esophageal motor disorders. Although the mechanisms of symptom generation in functional esophageal disorders are unclear, visceral hypersensitivity and hypervigilance may play a role. Therefore, treatment options include drugs and modalities that affect peripheral triggering and central perception. Further well-designed studies are needed to identify the mechanisms of symptom generation in, and to develop appropriate therapies for, functional esophageal disorders.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Anxiety
/
Chest Pain
/
Deglutition Disorders
/
Motor Disorders
/
Heartburn
/
Hypersensitivity
Limits:
Humans
Language:
Korean
Journal:
Korean Journal of Medicine
Year:
2017
Type:
Article
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