Serological Survey for Canine Parvovirus Type 2a (CPV-2a) in the Stray Dogs in South Korea

ABSTRACT

Canine parvovirus type-2 (CPV-2) is one of the major diarrhea-causing agents, inducing acute hemorrhagic gastroenteritis in puppies. In this study, we conducted a seroepidemiological survey of CPV-2a in stray dogs in South Korea. In total, 405 canine sera, collected between 2006 and 2007, were screened for the presence of antibodies against CPV-2a using a hemagglutination inhibition (HI) assay. The positive rate in stray dogs tested for CPV-2a was 93.8%. The regional CPV-2a prevalence was 100% (8/8) in Jeju, 95.1% (232/244) in Gyeonggi, 94.7% (36/38) in Jeonra, 92.9% (13/14) in Gangwon, 92.7% (38/41) in Chungcheong, and 88.3% (53/60) in Gyeungsang province. No significant difference in the seropositive rate was found between male (93.6%) and female (94.0%) dogs. Analysis of the distribution of HI titer against CPV-2a according to the age of the stray dogs showed a linear increase in seroprevalence with age, although the association with age was not statistically significant. The incidence of stray dogs showing an HI antibody titer above 15120 was estimated to be 26.2%. Thus, the presence of high HI antibody against CPV-2a may indicate circulation of CPV-2a in stray dogs.