Meningeal Relapse in a Patient with Acute Promyelocytic Leukemia: A Case Report and Review of the Literature
Journal of Korean Medical Science
;
: 311-314, 2004.
Article
in English
| WPRIM
| ID: wpr-211506
ABSTRACT
The involvement of central nervous system is rare in acute promyelocytic leukemia (APL). We report a APL patient of a 41 yr-old Korean male who presented with fever and petechia. Complete molecular remission was achieved with all-trans retinoic acid (ATRA), idarubicin, and cytarabine. Ten months later, he complained of a mild headache. The results of the physical examination and the complete blood counts were normal. The examination of cerebrospinal fluid showed the presence of promyelocyte. Bone marrow studies showed cytogenetic remission but with molecular relapse. He was treated with intrathecal and systemic chemotherapy.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Recurrence
/
Leukemia, Promyelocytic, Acute
/
Granulocyte Precursor Cells
/
Meninges
Limits:
Adult
/
Humans
/
Male
Language:
English
Journal:
Journal of Korean Medical Science
Year:
2004
Type:
Article
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