On the Origin of Oligodendrocytes
Yonsei Medical Journal
;
: 143-149, 1985.
Article
in English
| WPRIM
| ID: wpr-211662
ABSTRACT
Development and differentiation of astrocytes and oligodendrocytes (OC) in the developing human fetal spinal cord (HFSC) have been investigated by the correlative analysis of light microscopic, EM, Golgi and immunocytochemical studies. The evidence is presented to suggest, (a) that radial glia are the first distinguishable neuroglial element among the cells within the ventricular zone, (b) that radial glia contains astrocyte-specific glial fibrillary acidic protein (GFAP), (c) that radial glia undergoes transformation into astroglial cells, (d) that "transitional forms" possessing the light and EM features of both astroglial and oligodendroglial cells appear just prior to the onset of myelination, and (e) the myelin-forming OC are most likely derived from radial glial cells, either directly or through intermediated astroglial forms.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Spinal Cord
/
In Vitro Techniques
/
Microscopy, Electron
/
Oligodendroglia
/
Neuroglia
Limits:
Humans
Language:
English
Journal:
Yonsei Medical Journal
Year:
1985
Type:
Article
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