Electrophysiologic Finding of Retinitis Pigmentosa Inversus and Differential Diagnosis from Peripapillary Choroidal Dystrophy

ABSTRACT

The authors found 3 cases of retinitis pigmentosa inversus who had characteristics that age of onset is between fifth and sixth decade, retinal lesion was seen around the optic disc and along the retinal vascular arcade, margin is discrete, and peripheral retina is morphologically normal. The authors performed routine ophthalmic examination, fluorescein angiography, electroretinography, electro-oculography. Fluorescein angiogram of retinitis pigmentosa inversus showed diffuse hyperfluoresce due to retinal pigment epithelium atrophy and partical hypofluoreseenee due to choriocapillary atrophy. Characteristic electroretinogram findings were moderate decrease of rod function and mild decrease of cone function. The authors also experienced 1 cases of peripapillary choroidal dystrophy and could differentiate it from retinitis pigmentosa inversus. Peripapillary choroidal dystrophy showed similar that of retinitis pigmentosa inversus in electroretinogram test, but showed diffuse and typical hypofluo rescence due to choriocapillary and retinal pigment epithelium atrophy according to the retinal lesion.