The Experiences of the Emergency Antidote Stock and Delivery Service by the Korean Poison Information Center
Journal of The Korean Society of Clinical Toxicology
;
: 9-18, 2013.
Article
in Korean
| WPRIM
| ID: wpr-212417
ABSTRACT
PURPOSE:
Antidotes for toxicological emergencies can be life-saving. However, there is no nationwide stocking and delivery system for emergency antidotes in Korea. We report on a two-year experience of a nationwide stocking and delivery trial for emergency antidotes at emergency departments in Korea.METHODS:
An expert panel of clinical toxicologists reviewed and made a list of 15 stocked antidote. These antidotes were purchased or imported from other countries and delivered from 14 antidote stocking hospitals nationwide 24 hours per day, seven days per week.RESULTS:
From August 1, 2011 to April 30, 2013, 177 patients with acute poisoning, with a median age of 48.5 years, were administered emergency antidotes. The causes of poisoning were intentional in 52.0% and 88.0% were intentional as a suicide attempt. Regarding clinical severity, using the poisoning severity score, 40.7% of patients had severe to fatal poisoning and 39.0% had moderate poisoning according to clinical severity. The most frequent presenting symptom was neurologic deficit, such as altered mentality (62.7%). alerted mentality (62.7%). Emergency antidotes were administered as follows methylene blue (49 cases), flumazenil (31), N-acetylcysteine (25), glucagon (17), 100% ethanol (15), cyanide antidote kit (12), anti-venin immunoglobulin (5), pyridoxine (4), hydroxocobalamine (2), and deferoxamine (1). The median time interval from antidote request to delivery at the patient's bedside was 95 minutes (interquartile range 58.8-125.8).CONCLUSION:
Findings of this study demonstrated the possibility of successful operation of the nationwide system of emergency antidotes stocking and delivery in Korea.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Acetylcysteine
/
Pyridoxine
/
Suicide
/
Immunoglobulins
/
Glucagon
/
Flumazenil
/
Deferoxamine
/
Ethanol
/
Emergencies
/
Hydroxocobalamin
Limits:
Humans
Country/Region as subject:
Asia
Language:
Korean
Journal:
Journal of The Korean Society of Clinical Toxicology
Year:
2013
Type:
Article
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