Recent trends in hepatitis B virus infection in the general Korean population
The Korean Journal of Internal Medicine
;
: 413-419, 2013.
Article
in English
| WPRIM
| ID: wpr-212583
ABSTRACT
BACKGROUND/AIMS:
Hepatitis B virus (HBV) is the major cause of chronic liver disease in Korea, but viral prevalence has decreased because of hepatitis B vaccination programs. In this study, we investigated longitudinal changes in HBV in fection in the general Korean population.METHODS:
HBV surface antigen (hepatitis B surface antigen, HBsAg) seropositivity was assessed from the Korea National Health and Nutrition Examination Survey (I to V). In total, 50,140 subjects were tested for serum HBsAg positivity over a period of 12 years (1998 to 2010).RESULTS:
The prevalence of HBsAg seropositivity decreased over the study period. The rates of HBsAg carriers were 4.61% in 1998, 4.60% in 2001, 3.69% in 2005, 3.01% in 2008, and 2.98% in 2010 (p 0.05). Neither gender nor socioeconomic status were associated with the decreased prevalence of HBsAg carriers.CONCLUSIONS:
HBV infection has decreased in the Korean population since the advent of vaccination programs. However, the decrease is limited to the younger population, and viral persistence remains in the middle-aged and older population.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Socioeconomic Factors
/
Time Factors
/
Biomarkers
/
Chi-Square Distribution
/
Seroepidemiologic Studies
/
Prevalence
/
Cross-Sectional Studies
/
Health Surveys
/
Longitudinal Studies
/
Age Factors
Type of study:
Observational study
/
Prevalence study
/
Risk factors
Limits:
Adolescent
/
Adult
/
Aged
/
Child
/
Female
/
Humans
/
Male
Country/Region as subject:
Asia
Language:
English
Journal:
The Korean Journal of Internal Medicine
Year:
2013
Type:
Article
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