Effect of remifentanil on QT dispersion / 대한마취과학회지
Korean Journal of Anesthesiology
;
: 737-741, 2009.
Article
in Korean
| WPRIM
| ID: wpr-212853
ABSTRACT
BACKGROUND:
QT dispersion (QT(d)) is an indirect measure of the heterogeneity of ventricular repolarization and can be used as a risk factor for complex ventricular arrhythmias. We measured the effect of remifentanil on QT(d) and heart-rate corrected QT dispersion (QT(cd)).METHODS:
Sixty ASA class I and II patients, who were between 20 and 60 years old, and who were scheduled for general anesthesia, were studied. After the patient entered the operating room, a 12 lead EKG recording was taken and intravenous infusion of remifentanil was started. The infusion rate was 0.1 microg/kg/min in group 1 and 0.2 microgram/kg/min in group 2. Another EKG recording was taken 10 minutes after infusion had started.RESULTS:
In both groups, QT(d) following remifentanil infusion was not significantly different than control values (76.6 +/- 23.3 ms vs 81.8 +/- 34.9 ms, P = 0.459 in group 1; 70.7 ms +/- 29.7 ms vs 73.7 ms +/- 37.1 ms, P = 0.734 in group 2). Neither was QT(cd) (83.2 ms +/- 25.2 ms vs 89.6 ms +/- 36.2 ms, P = 0.371 in group 1; 81.0 ms +/- 35.2 ms vs 83.4 ms +/- 40.9 ms, P = 0.829 in group 2).CONCLUSIONS:
Remifentanil infusion at a rate less than 0.2 microg/kg/min does not change QT(d) or QT(cd).
Full text:
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Index:
WPRIM (Western Pacific)
Main subject:
Operating Rooms
/
Piperidines
/
Arrhythmias, Cardiac
/
Population Characteristics
/
Infusions, Intravenous
/
Risk Factors
/
Electrocardiography
/
Heart Conduction System
/
Anesthesia, General
Type of study:
Etiology study
/
Risk factors
Limits:
Humans
Language:
Korean
Journal:
Korean Journal of Anesthesiology
Year:
2009
Type:
Article
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