Comparative Study of Ondansetron versus Droperidol versus Placebo to Prevent Postoperative Nausea and Vomiting after Strabismus in Children / 대한마취과학회지
Korean Journal of Anesthesiology
;
: 1639-1645, 1994.
Article
in Korean
| WPRIM
| ID: wpr-213258
ABSTRACT
Postoperative nausea and vomiting is a troublesome problem in pediatric patients undergo- ing strabismus surgery. We compared the effects of ondansetron with those of droperidol and placebo within the 24hrs postoperative period. 54 children, who admitted to Presbyteri- an Medical Center to receive strabismus operations, with ASA physical status 1, were as- signed to one of three groups according to uncontrolled parallel comparative study design. A standard anesthetic technique consisting of thiopental-vecuronium for induction and N2O-O2-enflurane for maintenance of anesthesia was used. The data showed that ondansetron 0. 067mg/kg i.v. before induction was significantly more effective in preventing emesis (n=19, 100%) than placebo(n=17, 58.8%). But, there was no significant difference between droperidol group and placebo group. In conclusion, ondansetron(0.067mg/kg) given intravenously before induction to prevent postoperative nausea and vomiting in patients undergoing elective strabismus surgery in children was effective.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Postoperative Period
/
Vomiting
/
Strabismus
/
Ondansetron
/
Postoperative Nausea and Vomiting
/
Droperidol
/
Anesthesia
/
Nausea
Type of study:
Controlled clinical trial
Limits:
Child
/
Humans
Language:
Korean
Journal:
Korean Journal of Anesthesiology
Year:
1994
Type:
Article
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