Your browser doesn't support javascript.
loading
The Effects of Combined Use of Hemodilution and Induced Hypotension on Hemodynamics and Oxygen Carrying Capacity in the Patients Under Posterior Spinal Fusion / 대한마취과학회지
Korean Journal of Anesthesiology ; : 1620-1627, 1994.
Article in Korean | WPRIM | ID: wpr-213261
ABSTRACT
To decrease homologous transfusion and bleeding, hemodilution may be combined with in- duced hypotension. The effects of the above method on hemodynamics and oxygen carrying capacity in human is not studied. Ten patients, age 16-62 yr, having posterior spinal fusion, were studied. Acute preoperative hemodilution to hematocrit 27% with infusion of 10% pentastarch was performed in the patients. After induction of anesthesia and positioning we deereased mean arterial pressure to around 55mmHg by isoflurane and sodium nitroprusside. We observed the changes of hemodynamics and oxygen carrying capacity before hemodilution, after hemodilution, after induced hypotension and before the end of operation. After hemodilution, heart rate and arterial pressure were not changed significantly. Cardiac output and central venous pressure increased significantly. Systemic vascular resistance decreased significantly. There were no significant changes in arterial and mixed venous blood gas analysis. Oxygen flux was not changed significantly. Oxygen consumption and oxygen extraction ratio increased significantly but remained within normal range. After induced hypotension, heart rate was not changed. Cardiac output became lower than that after hemodilution, but was not different from the preoperative value. Systemic vascular resistance became lower than the preoperative value. There were no significant changes in arterial and mixed venous blood gas analysis except for mixed venous blood oxygen saturation. The mixed blood oxygen saturation increased to the preoperative level. Oxygen flux decreased, but oxygen consumption and oxygen extraction ratio were not significantly different from the preoperative values. There were no clinically significant changes in hemodynamics and oxygen carrying capacity before the end of operation. By the above results, we concluded that the combined use of hemodilution and induced hypotension is safe in the aspect of hemodynamics and oxygen carrying capacity.
Subject(s)

Full text: Available Index: WPRIM (Western Pacific) Main subject: Oxygen / Oxygen Consumption / Reference Values / Spinal Fusion / Vascular Resistance / Blood Gas Analysis / Nitroprusside / Cardiac Output / Central Venous Pressure / Hydroxyethyl Starch Derivatives Limits: Humans Language: Korean Journal: Korean Journal of Anesthesiology Year: 1994 Type: Article

Similar

MEDLINE

...
LILACS

LIS

Full text: Available Index: WPRIM (Western Pacific) Main subject: Oxygen / Oxygen Consumption / Reference Values / Spinal Fusion / Vascular Resistance / Blood Gas Analysis / Nitroprusside / Cardiac Output / Central Venous Pressure / Hydroxyethyl Starch Derivatives Limits: Humans Language: Korean Journal: Korean Journal of Anesthesiology Year: 1994 Type: Article