Change of Quality of Life in Children with ADHD after 12 Weeks OROS-Methylphenidate Treatment
Journal of the Korean Academy of Child and Adolescent Psychiatry
;
: 103-108, 2012.
Article
in Korean
| WPRIM
| ID: wpr-213367
ABSTRACT
OBJECTIVES:
The aim of this study is to investigate the effectiveness of treatment with osmotic-release oral system methylphenidate (OROS-MPH) on quality of life (QOL) in children with attention-deficit hyperactivity disorder (ADHD). Another aim is to assess the relationship between change in QOL and other factors including children's symptoms and academic performance or parents' depression and parenting stress.METHODS:
A total of 111 medication-naive children with ADHD in a multicenter, open-label, 12-week trial of OROS-MPH completed an evaluation using diverse rating scales at two time points; at baseline and after 12 weeks of treatment. Scales for investigation of children included the Parent Report Form-Children's Health and Illness Profile-Children's Edition (PRF-CHIP-CE) on QOL, the ADHD Rating Scale-IV on symptoms, and the Academic Performance Rating Scale (APRS). The Beck Depression Inventory and Parenting Stress Index were used for assessment of their parents.RESULTS:
Total scores for mean PRF-CHIP-CE increased from 207.9+/-26.7 at baseline to 226.3+/-25.9 after 12 weeks of treatment (p<.001). The change of APRS showed the strongest correlation with the increment of PRF-CHIP-CE scores (Pearson coefficient= 0.561, p<.001), even after controlling for other factors (partial correlation coefficient=0.420, p<.001).CONCLUSION:
Treatment with MPH-OROS results in improvement of QOL in children with ADHD in Korea. The advance in academic performance plays a key role in this change of QOL.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Parents
/
Quality of Life
/
Weights and Measures
/
Parenting
/
Depression
/
Korea
/
Methylphenidate
Type of study:
Controlled clinical trial
Limits:
Child
/
Humans
Country/Region as subject:
Asia
Language:
Korean
Journal:
Journal of the Korean Academy of Child and Adolescent Psychiatry
Year:
2012
Type:
Article
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