FDG-PET Scan in Patients with Cervical Cancer: Experience in Patients with Clinically No Evidence of Disease / 대한산부인과학회잡지
Korean Journal of Obstetrics and Gynecology
;
: 2055-2061, 1999.
Article
in Korean
| WPRIM
| ID: wpr-213674
ABSTRACT
OBJECTIVE:
The purpose of this study was to investigate the clinical feasibility of FDG-PET (Positron Emission Tomography) scan in patients with clinically no evidence of disease after treatment of cervical cancer.METHODS:
One hundred and one patients with clinically NED(no evidence of disease) state after treatment of cervical cancer underwent PET scan. FDG-PET scan was obtained with a GE Advance Scanner, beginning at 50 minutes after injection of 370-555 MBq(10-15 mCi) of 18F FDG. Regional scan was also obtained with emission image. Uptake exceeding 3.0 SUV was determined as a positive finding. Recurrence was confirmed by CT, MRI, and needle biopsy if possible.RESULTS:
Among 101 patients showing no evidence of disease, 17 patients(16.8%) showed abnormal PET scan findings. Clinically, 8 patients(7.9%) were confirmed to have recurrent lesion by CT, MRI or by needle biopsy. PET scan could detect recurrent lesions in the mediastinum or lung(10/17), pelvis(7/17), and supraclavicular lymph node(2/17). The sensitivity and specificity of PET scan in patients with cervical cancer showing no evidence of disease were 100% and 90.3%, respectively. The positive predictive value, negative predictive value and false positive rate were 47.1%, 100% and 52.9%.CONCLUSION:
PET scan could detect 7.9% of early recurrence in patients with cervical cancer with NED status. FDG-PET scan may be a useful method in detecting metastases or recurrence of a cervical cancer showing no evidence of disease by routine conventional imaging studies.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Recurrence
/
Biopsy, Needle
/
Magnetic Resonance Imaging
/
Uterine Cervical Neoplasms
/
Sensitivity and Specificity
/
Positron-Emission Tomography
/
Mediastinum
/
Neoplasm Metastasis
Type of study:
Diagnostic study
Limits:
Humans
Language:
Korean
Journal:
Korean Journal of Obstetrics and Gynecology
Year:
1999
Type:
Article
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