Levofloxacin and Torsades de Pointes / 결핵및호흡기질환
Tuberculosis and Respiratory Diseases
;
: 474-479, 2010.
Article
in Korean
| WPRIM
| ID: wpr-214076
ABSTRACT
Torsades de pointes associated with a prolonged QT interval is a life-threatening arrhythmia, which may be induced by any of the following drugs, electrolyte imbalances, severe bradycardia and intracranial hemorrhage. Torsades de pointes is characterized by beat-to-beat variations in the QRS complexes in any ECG leads with rates of 200~250 per minute. Fluoroquinolones are widely used and well tolerated antibacterial agents. However, prolongation of the QT interval leads rarely to Torsades de pointes as a significant adverse effect. So, it should be used with caution in high-risk patients for developing Torsades de pointes. We report one case of 67-year old man with contact burns who experienced Torsades de pointes, which probably resulted from the use of levofloxacin, and no further episode occurred after its withdrawal.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Arrhythmias, Cardiac
/
Bradycardia
/
Burns
/
Ofloxacin
/
Torsades de Pointes
/
Intracranial Hemorrhages
/
Fluoroquinolones
/
Electrocardiography
/
Anti-Bacterial Agents
Limits:
Humans
Language:
Korean
Journal:
Tuberculosis and Respiratory Diseases
Year:
2010
Type:
Article
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