Clinicopathologic Characteristics and Treatment Outcomes of Penile Cancer
The World Journal of Men's Health
;
: 28-33, 2017.
Article
in English
| WPRIM
| ID: wpr-214132
ABSTRACT
PURPOSE:
The aim of this study was to assess the clinicopathologic characteristics of penile cancer, including patterns of therapy, oncologic results, and survival. MATERIALS ANDMETHODS:
Between January 2005 and July 2015, 71 patients at 6 institutions who had undergone penectomy or penile biopsy were enrolled. Their medical records were reviewed to identify the mode of therapy, pathology reports, and cancer-specific survival (CSS) rate.RESULTS:
Clinicopathologic and outcome information was available for 52 male patients (mean age, 64.3 years; mean follow-up, 61.4 months). At presentation, 17 patients were node-positive, and 4 had metastatic disease. Management was partial penectomy in 34 patients, total penectomy in 12 patients, and chemotherapy or radiotherapy in 6 patients. The pathology reports were squamous cell carcinoma in 50 patients and other types of carcinoma in the remaining 2 patients. Kaplan-Meier survival analysis showed a 5-year CSS rate of 84.0%. In univariate and multivariate analyses, the American Joint Committee on Cancer (AJCC) stage and pathologic grade were associated with survival.CONCLUSIONS:
Partial penectomy was the most common treatment of penile lesions. The oncologic outcomes were good, with a 5-year CSS of 84.0%. The AJCC stage and pathologic grade were independent prognostic factors for survival.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pathology
/
Penile Neoplasms
/
Prognosis
/
Radiotherapy
/
Biopsy
/
Carcinoma, Squamous Cell
/
Medical Records
/
Multivariate Analysis
/
Follow-Up Studies
/
Treatment Outcome
Type of study:
Observational study
/
Prognostic study
Limits:
Humans
/
Male
Language:
English
Journal:
The World Journal of Men's Health
Year:
2017
Type:
Article
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