Targeted Molecular Imaging
Korean Journal of Radiology
; : 201-210, 2003.
Article
in En
| WPRIM
| ID: wpr-214910
Responsible library:
WPRO
ABSTRACT
Molecular imaging aims to visualize the cellular and molecular processes occurring in living tissues, and for the imaging of specific molecules in vivo, the development of reporter probes and dedicated imaging equipment is most important. Reporter genes can be used to monitor the delivery and magnitude of therapeutic gene transfer, and the time variation involved. Imaging technologies such as micro-PET, SPECT, MRI and CT, as well as optical imaging systems, are able to non-invasively detect, measure, and report the simultaneous expression of multiple meaningful genes. It is believed that recent advances in reporter probes, imaging technologies and gene transfer strategies will enhance the effectiveness of gene therapy trials.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Diagnostic Imaging
/
Genetic Therapy
/
Gene Expression
/
Apoptosis
/
Genes, Reporter
/
Neovascularization, Physiologic
/
Contrast Media
/
Molecular Biology
Type of study:
Diagnostic_studies
Limits:
Animals
/
Humans
Language:
En
Journal:
Korean Journal of Radiology
Year:
2003
Type:
Article