Three Cases of Clear Cell Acanthoma on Nipple and Areola / 대한피부과학회지

ABSTRACT

Clear cell acanthoma is a relatively uncommon benign disease, which usually presents as solitary lesions, often localized on the lower legs of middle aged or elderly individuals1. Clinically it presents as a flat or dome-shaped, sharply demarcated papule or nodule. Histopathologic findings are composed of clear cells within sharply demarcated area of the epidermis. We report three cases of clear cell acanthoma developed on the nipples and areolar areas of the young women. These cases should be differentiated from various diseases showing clinically benign eczematous feature. In conclusion, clear cell acanthoma could be included in the differential diagnosis of eczema, and it is suggested that biopsies specimen should include the lesion as well as the normal tissue.