Mean Macular Volume in Normal Korean Eyes Measured by Spectral-domain Optical Coherence Tomography

ABSTRACT

PURPOSE: To evaluate the mean macular volume in normal Korean eyes using spectral-domain optical coherence tomography. METHODS: The present study consisted of 132 patients (212 eyes) with no ophthalmic evidence of retinopathy and who had a best corrected visual acuity of 1.0 or better. The total macular volume was measured using spectral-domain optical coherence tomography and was analyzed according to age group, sex, degree of refractive error and presence of systemic disease such as diabetes and hypertension. RESULTS: The mean total macular volume of all subjects was 10.07 +/- 0.45 mm3, with means of 10.13 +/- 0.40 mm3, 10.05 +/- 0.43 mm3 and 9.97 +/- 0.58 mm3 measured for the respective A, B, and C age groups. There was a significant difference between male and female patients. In addition, there was a significant difference between diabetic patients in group C and normal subjects. However, there was no significant difference according to degree of refractive error. CONCLUSIONS: The measured value of mean macular volume in normal Korean eyes can be expected to provide a standard value for diagnosing retinal disease and the need for careful follow-up.