Korean Red Cross HLA-Matched Platelet Donor Registry / 대한수혈학회지
Korean Journal of Blood Transfusion
;
: 291-299, 2015.
Article
in Korean
| WPRIM
| ID: wpr-215690
ABSTRACT
BACKGROUND:
Transfusion of HLA-matched platelets is required when development of platelet refractoriness occurs after repeated platelet transfusion. This study was conducted to establish a HLA-matched platelet donor registry to supply matched platelets to patients who develop platelet refractoriness.METHODS:
HLA-matched platelet donors were recruited among plateletpheresis donors. HLA-A and HLA-B antigen types of recruited donors were tested using a polymerase chain reaction-sequence specific oligonucleotide probe method.RESULTS:
A total of 1,029 plateletpheresis donors were recruited. HLA-A and HLA-B antigen frequencies of recruited donors were similar to those of previously reported HLA antigen frequencies of Koreans. During the study period, a patient with platelet refractoriness recovered after receiving six units of HLA-matched platelets.CONCLUSION:
During this study 1,029 donors were registered as HLA-matched platelet donors and a patient with platelet refractoriness received HLA-matched platelets using this registry. Supply of HLA-matched platelets will be facilitated by continuous expansion of the number of registered HLA-matched platelet donors, development of a program for management and searching for HLA-matched donors, and establishment of a request-supply system between hospitals and the Korean Red Cross through further studies.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Red Cross
/
Tissue Donors
/
Blood Platelets
/
HLA-A Antigens
/
HLA-B Antigens
/
Plateletpheresis
/
Platelet Transfusion
Limits:
Humans
Language:
Korean
Journal:
Korean Journal of Blood Transfusion
Year:
2015
Type:
Article
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