Two Cases of Anti-p200 Pemphigoid / 대한피부과학회지
Korean Journal of Dermatology
;
: 821-825, 2008.
Article
in Korean
| WPRIM
| ID: wpr-215776
ABSTRACT
Anti-p200 pemphigoid is a recently defined subepidermal immunobullous disease. Most anti-p200 pemphigoid patients show the clinical features of bullous pemphigoid, dermatitis herpetiformis and linear IgA disease. It is characterized by the binding of circulating IgG autoantibodies to the dermal side of 1 M NaCl split skin, and by reactivity of these autoantibodies to a unique 200-kD antigen on immunoblot of dermal extract. On immunoelectron microscopic examination, these autoantibodies deposit at the lamina lucida-lamina densa interface. Herein, we report two cases of anti-p200 pemphigoid, as well as their favorable response to treatment with systemic corticosteroid, colchicine and dapsone.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Skin
/
Autoantibodies
/
Immunoglobulin A
/
Immunoglobulin G
/
Colchicine
/
Dermatitis Herpetiformis
/
Pemphigoid, Bullous
/
Dapsone
Limits:
Humans
Language:
Korean
Journal:
Korean Journal of Dermatology
Year:
2008
Type:
Article
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