Clinical Diagnostic Application of Serum Cholinesterase

ABSTRACT

Serum cholinesterase and other commonly employed function tests were determined in 12 patients with nephrotic syndrome, 17 patients with infectious hepatitis and 7 patients with acute glomerulonephritis who were available for se5rial studies the evaluation of which was helpful in diagnosis, management and prognosis of various disease. The results were as follows. 1) Serum cholinesterase activity in patients with nephrotic syndrome was much higher than normal. Thereafter the activity progressively turned into the normal. Value associated with improvement of the values of other function tests and clinical courses in case which responded positively to treatment. 2) In patients with infectious hepatitis serum cholinesterase was lower than the normal value but the steadily rose from low to normal value according to improvement of clinical courses. In two patients with postnecrotic cirrhosis and toxic hepatitis the activity was much lower than normal but other function tests showed normal range. 3) Serum cholinesterase in patients with glomerulonephritis showed atypical charges during clinical courses.