Gallium-67 Scintigraphy in Glomerular Disease / 대한내과학회지
Korean Journal of Medicine
;
: 509-516, 1999.
Article
in Korean
| WPRIM
| ID: wpr-216269
ABSTRACT
OBJECTIVES:
Gallium 67(Ga-67) scintigraphy has been used to diagnose inflammatory and neoplastic diseases. We undertook a study to determine the clinical value of Ga- 67 renal scan in patients with various glomerular diseases.METHODS:
Ga-67 scintigraphy was performed in 48 patients with various biopsy proven forms of renal diseases. Renal uptake in 48 patients images was graded as follow Grade 0 = not visualization at 48 hours 1 = faintly visualize 2 = equal to uptake in spine 3 = greater than over the spine 4 = greater than activity over the liver.RESULTS:
1) Of the 48 patients, 31 were male, and mean age was 32 years. 11 patients had hypertension and 29 patients had hematuria. 2) Positive scintigram were seen in 40 of 48(83%) cases. In results of renal biopsy, IgA nephropathy(IgAN) was 15 patients, minimal change disease(MCD) was 14, focal segmental glomerulosclerosis (FSGS) was 8, membranoproliferative glomerulonephritis (MPGN) was 3, lupus nephritis(LN) was 3, poststreptococcal glomerulonephritis(PSGN) was 3 and membranous glomerulonephritis(MGN) was 2. 3) In 26 patients (54%) with nephrotic-range proteinuria, Grade 2 or higher renal uptake was observed in 9 (75%) of MCD, 5(100%) of FSGS, 2(100%) of LN and 3(75%) of IgAN. 4) In comparision nephrotics with non-nephrotics at biopsy, renal Ga-67 uptake in who patients had nephrotic-range proteinuria was correlated with clinical severity determined by serum albumin, serum total cholesterol and 24 hours urine protein excretion.CONCLUSIONS:
Renal Ga-67 scintigraphy may be able to be a predictor in the assessment for severity of nephrotic syndrome.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Proteinuria
/
Spine
/
Biopsy
/
Immunoglobulin A
/
Serum Albumin
/
Glomerulosclerosis, Focal Segmental
/
Glomerulonephritis, Membranoproliferative
/
Radionuclide Imaging
/
Cholesterol
/
Gallium
Limits:
Humans
/
Male
Language:
Korean
Journal:
Korean Journal of Medicine
Year:
1999
Type:
Article
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