Effect of Capsaicin on Immune Responses, Anaphylaxis and Tumorigenesis in Mice / 대한면역학회지
Korean Journal of Immunology
;
: 229-244, 1997.
Article
in Korean
| WPRIM
| ID: wpr-216317
ABSTRACT
It has been known that the interconnection between the gervous, endocrine and immune system are largely mediated through regulatory soluble factors such as neruopeptides, cytokines and hormones. Capsaicin, the pungent principle of hot peppers, is a neurotoxin that affects primary sensory neurons of the C and A-b type and depletes primary sensory neurons (polymodal nociceptors) of neuropeptides like tachykinin. In this study capsaicin was used to explore the possible role of the neruons on the expression of cellular and humoral immune responses and TNF-a prodcution. Mice were pretreated with s.c. injections in the neck region with a single dose of 100 u,g of capsaicin per mouse before immunization. ...continue...
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Sensory Receptor Cells
/
Neuropeptides
/
Capsaicin
/
Tachykinins
/
Cytokines
/
Immunization
/
Immunity, Humoral
/
Carcinogenesis
/
Anaphylaxis
/
Immune System
Limits:
Animals
Language:
Korean
Journal:
Korean Journal of Immunology
Year:
1997
Type:
Article
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