Treatment options after sorafenib failure in patients with hepatocellular carcinoma
Clinical and Molecular Hepatology
;
: 273-279, 2017.
Article
in English
| WPRIM
| ID: wpr-216539
ABSTRACT
Second line therapy after failure of sorafenib continues to be under study. Prognosis of hepatocellular carcinoma is measured in months, with median overall survival reaching 10.7 months with sorafenib. Because of the modest net benefit sorafenib has contributed, and rising incidence of hepatocellular carcinoma in the world, continued efforts are ongoing to look for efficient upfront, second line, or combination therapies. Herein we review the most relevant to date published literature on treatment options beyond sorafenib, reported studies, ongoing investigational efforts, and possibilities for future studies in advanced hepatocellular carcinoma.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Prognosis
/
Incidence
/
Carcinoma, Hepatocellular
/
Immunotherapy
Type of study:
Incidence study
/
Prognostic study
Limits:
Humans
Language:
English
Journal:
Clinical and Molecular Hepatology
Year:
2017
Type:
Article
Similar
MEDLINE
...
LILACS
LIS