Carboplatin and paclitaxel as an initial treatment in patients with stage IVb cervical cancer: a report of 7 cases and a review of the literature / 부인종양
Journal of Gynecologic Oncology
;
: 93-96, 2010.
Article
in English
| WPRIM
| ID: wpr-217480
ABSTRACT
OBJECTIVE:
The aim of this study is to evaluate the efficacy of carboplatin-paclitaxel (TC) as an initial treatment in patients with the International Federation of Gynecology and Obstetrics (FIGO) stage IVb cervical cancer.METHODS:
We retrospectively reviewed seven patients with stage IVb cervical cancer who have been primarily treated with TC. The activity and the toxicity were evaluated. Response rate was the main endpoint.RESULTS:
Overall, the treatment of TC was well tolerated. The overall response rate was 71.4% (2 complete response, 3 partial response). Although grade 3-4 hematologic toxicities were observed in 3 out of 7 patients (42.8%), no patients experienced grade 3-4 non-hematologic toxicities. When we combined our present results with the previous reports, the overall response rate of TC is 63.6%.CONCLUSION:
TC is active and well tolerated in patients FIGO stage IVb cervical cancer. This combination may be considered as an initial treatment regimen in this patient population.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Uterine Cervical Neoplasms
/
Retrospective Studies
/
Carboplatin
/
Paclitaxel
/
Gynecology
/
Obstetrics
Type of study:
Observational study
Limits:
Humans
Language:
English
Journal:
Journal of Gynecologic Oncology
Year:
2010
Type:
Article
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