Skin Necrosis after a Low-Dose Vasopressin Infusion through a Central Venous Catheter for Treating Septic Shock
The Korean Journal of Internal Medicine
;
: 287-290, 2006.
Article
in English
| WPRIM
| ID: wpr-217641
ABSTRACT
This is a report on a case of severe skin necrosis in a vasodilatory septic shock patient after the infusion of low-dose vasopressin through a central venous catheter. An 84-year-old male was hospitalized for edema on both legs at Asan Medical Center, Seoul, Korea. On hospital day 8, the patient began to complain of dyspnea and he subsequently developed severe septic shock caused by E. coli. After being transferred to the medical intensive care unit, his hypotension, which was refractory to norepinephrine, was controlled by an infusion of low-dose vasopressin (0.02 unit/min) through a central venous catheter into the right subclavian vein. After the infusion of low-dose vasopressin, severe skin necrosis with bullous changes developed, necessitating discontinuation of the low-dose vasopressin infusion. The patient expired from refractory septic shock. Although low-dose vasopressin can control hypotension in septic shock patients, low-dose vasopressin must be used with caution because ischemic complications such as skin necrosis can develop even with administration through a central venous catheter.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Shock, Septic
/
Skin
/
Vasoconstrictor Agents
/
Infusions, Intravenous
/
Vasopressins
/
Catheterization, Central Venous
/
Fatal Outcome
/
Dose-Response Relationship, Drug
/
Necrosis
Limits:
Aged
/
Aged80
/
Humans
/
Male
Language:
English
Journal:
The Korean Journal of Internal Medicine
Year:
2006
Type:
Article
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