A comparison of the suppression of cough reflex by intravenous lidocaine and remifentanil prior to extubation of the endotracheal tube / 대한마취과학회지
Korean Journal of Anesthesiology
;
: 452-457, 2008.
Article
in Korean
| WPRIM
| ID: wpr-217968
ABSTRACT
BACKGROUND:
Cough reflex in response to extubation of the endotracheal tube is common; however, the effect of remifentanil on cough reflex is uncertain. Therefore, we evaluated the effect of lidocaine and remifentanil on cough reflex following extubation.METHODS:
Forty adult patients scheduled to undergo elective surgery in two hours were enrolled in this study. All patients received a standard anesthetic protocol. Following surgery, the patients were randomly divided into two groups, Group L (n = 20), which received 1.5 mg/kg of 2% lidocaine intravenously, and Group R (n = 20), which received 0.5 microgram/kg remifentanil intravenously. Treatment was administered immediately after the patients opened their eyes, after which extubation was performed. We then evaluated breath holding and recorded the number of coughs at 5 minutes, 15 minutes and 30 minutes after extubation. In addition, we checked for sore throat 30 minutes after extubation.RESULTS:
The number of coughs was significantly lower in Group R than in Group L at 5 minutes after extubation. However, there was no significant difference in the number of coughs in Group R and Group L at any other times evaluated.CONCLUSIONS:
There are no significant differences in suppression of the cough reflex in response to treatment with lidocaine and remifentanil.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Piperidines
/
Reflex
/
Pharyngitis
/
Cough
/
Eye
/
Breath Holding
/
Lidocaine
Type of study:
Practice guideline
Limits:
Adult
/
Humans
Language:
Korean
Journal:
Korean Journal of Anesthesiology
Year:
2008
Type:
Article
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