Approximate entropy as the measurement of the electroencephalographic effect during sevoflurane induction / 대한마취과학회지
Korean Journal of Anesthesiology
;
: 404-411, 2008.
Article
in English
| WPRIM
| ID: wpr-217976
ABSTRACT
BACKGROUND:
The processed electroencephalograms are useful surrogate measures of quantification of volatile anesthetics effect. We hypothesized that there is a certain relationship between the end-tidal concentration of sevoflurane and approximate entropy (ApEn). The aim of this study was to investigate the effect of sevoflurane on ApEn during induction.METHODS:
Fourteen patients were enrolled. With recording of the electroencephalogram at the F3, F4, P3, and P4 montages, anesthesia was induced by increasing the vapor setting of sevoflurane by 1 vol% up to 8 vol% via a facemask. When the end-tidal concentration of sevoflurane did not show any further change, we increased vapor setting of sevoflurane by 1 vol%. When the end-tidal concentration of sevoflurane did not show any further change with 8 vol% of sevoflurane vapor setting, measurement of electroencephalogram was finished. The relation between end-tidal sevoflurane concentration and ApEn was tested by Spearman correlation.RESULTS:
ApEn showed a significant correlation (R = -0.7551, P < 0.0001) with end-tidal sevoflurane concentration. The final pharmacodynamic parameters estimated by a sigmoid E(max) model were described as follows E(0) = 0.91, E(max) = 0.28, C(e50) = 1.36 vol%, gamma = 1.27, kappa(e0) = 0.67 min(-1).CONCLUSIONS:
Sevoflurane induction with gradual increase of end-tidal sevoflurane concentration increases the amount of regularity in approximate entropy.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Colon, Sigmoid
/
Entropy
/
Electroencephalography
/
Anesthesia
/
Anesthetics
/
Methyl Ethers
Limits:
Humans
Language:
English
Journal:
Korean Journal of Anesthesiology
Year:
2008
Type:
Article
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