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A Case of Hemosiderosis due to Multiple Transfusion / 대한피부과학회지
Korean Journal of Dermatology ; : 1127-1130, 1994.
Article in Korean | WPRIM | ID: wpr-218165
ABSTRACT
Hemosiderosis is a disorder characterized by deposits of hemosicerin in multiple organs without organ dysfunction or injury. The color of the skin becomes brown, espeially on sun exposured areas. Mucous mernbranes are also affected in up to 5-25% of cases. A 43-year-old woman visited our clinic due to generalized brown colotation of her skin, including conjunct we and oral mucous mernbrane which she had had for 10 months. She had been treated with multiple he nodialysis combined with periodic transfusion for renal failure 3 times a month during the last 5 yeadrs Her plasma ferrit in level was elevated markedly and TIBC decreased, but cortisol and ACTH levels were within normal limits, Histopathologic findings of the neck skin showed hyperpigmentation of basal layer and deposition of brown pigment wrthin and around the sweat glands. In Fontana-Masson stain, the lower epidermis showed a massive deposition of melanin. Prussian blue stain revealei hemosiderin within snd around, the sweat glands. Hemosiderin could also be noticed on specirnens of thliver biopsy. The patient improved progressively after the rstriction of trasnfusion and treatment of renal failure.
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Full text: Available Index: WPRIM (Western Pacific) Main subject: Plasma / Skin / Sweat Glands / Biopsy / Hydrocortisone / Solar System / Hyperpigmentation / Adrenocorticotropic Hormone / Epidermis / Renal Insufficiency Limits: Adult / Female / Humans Language: Korean Journal: Korean Journal of Dermatology Year: 1994 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Plasma / Skin / Sweat Glands / Biopsy / Hydrocortisone / Solar System / Hyperpigmentation / Adrenocorticotropic Hormone / Epidermis / Renal Insufficiency Limits: Adult / Female / Humans Language: Korean Journal: Korean Journal of Dermatology Year: 1994 Type: Article