Association between the Red Cell Distribution Width and Vasospastic Angina in Korean Patients
Yonsei Medical Journal
;
: 614-620, 2016.
Article
in English
| WPRIM
| ID: wpr-21855
ABSTRACT
PURPOSE:
The association between the red cell distribution width (RDW) and vasospastic angina (VSA) has not been elucidated. We investigated the association of the RDW with the incidence and angiographic subtypes of VSA in Korean patients. MATERIALS ANDMETHODS:
A total of 460 patients who underwent intracoronary ergonovine provocation tests were consecutively enrolled and classified into two groups the VSA group (n=147, 32.0%) and non-VSA group (n=313, 68.0%). The subjects were classified into 3 subgroups (tertiles) according to the baseline level of RDW assessed before the angiographic provocation test.RESULTS:
The VSA group had a higher RDW than the non-VSA group (12.9±0.8% vs. 12.5±0.7%, p=0.013). The high RDW level demonstrated an independent association with the high incidence of VSA [second tertile hazard ratio (HR) 1.96 (1.13-2.83), third tertile HR 2.33 (1.22-3.47), all p<0.001]. Moreover, the highest RDW tertile level had a significant association with the prevalence of the mixed-type coronary spasm [HR 1.29 (1.03-1.59), p=0.037].CONCLUSION:
The high level of RDW was significantly associated with the prevalence of VSA and the high-risk angiographic subtype of coronary spasm, suggesting that a proactive clinical investigation for VSA could be valuable in Korean patients with an elevated RDW.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Proportional Hazards Models
/
Incidence
/
Prevalence
/
Coronary Angiography
/
Coronary Vasospasm
/
Erythrocyte Indices
/
Republic of Korea
/
Angina Pectoris
Type of study:
Incidence study
/
Prevalence study
/
Prognostic study
/
Risk factors
Limits:
Aged
/
Aged80
/
Female
/
Humans
/
Male
Country/Region as subject:
Asia
Language:
English
Journal:
Yonsei Medical Journal
Year:
2016
Type:
Article
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