The Effect of Palliative Transurethral Resection of Prostate(Channel TURP) for Acute Urinary Retention in Patients with Metastatic Prostatic Cancer

ABSTRACT

PURPOSE: Obstructive voiding difficulties were frequent in the patients with metastatic prostatic cancer, and sometimes acute urinary retention may be developed even though medical treatments. We performed channel transurethral resection of prostate(TURP) as palliative treatment for those patients and reported the results. MATERIALS AND METHODS: Fifteen patients with metastatic prostatic cancer were taken TURP aiming for relief of infravesical obstruction. All patients were under the anti-androgen hormonal therapy and had sudden onset of acute urinary retention. TURP was done under general or epidural anesthesia. After TURP, 30~50 cc ballooning urethral Foley catheter was placed for 4 days. We analyzed voiding parameters comparatively before and 3 months after TURP. RESULTS: The mean age of patients was 75.6+/-5.7 years old. Mean prostatic volume was 47.8+/-1.4 cc. Mean resected prostatic tissue was 6.4+/-2.1 cc. All patients had stage D prostatic cancer. Mean serum PSA was 75.2+/-73.8 ng/ml and mean gleason score was 7.8+/-0.9. After TURP, mean international prostatic symptom score(IPSS) was improved from 25.5+/-2.0 to 13.8+/-2.0, mean quality of life score(QOL) was improved from 4.4+/-0.5 to 2.0+/-0.5, and mean maximum uroflow rate was increased from 5.0+/-1.1 ml/sec to 6.0+/-1.6 ml/sec. All patients did not have any complications according to TURP. CONCLUSION: In patients with metastatic prostatic cancer, channel TURP could be considered as a treatment option to relieve severe obstructive voiding difficulty.