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Overview of Pediatric Testicular Tumors in Korea
Korean Journal of Urology ; : 789-796, 2014.
Article in English | WPRIM | ID: wpr-219574
ABSTRACT
Prepubertal testicular tumors are rare compared with postpubertal testicular tumors. The incidence of prepubertal testicular tumors peaks at 2 years of age, tapers off after 4 years of age, and then begins to rise again at puberty. Prepubertal and postpubertal testicular tumors show many differences, including the typical tumor histology, molecular biological differences, and the malignant potential of tumors at different ages. Pediatric testicular tumors are classified as benign or malignant on the basis of their clinical behavior and histologically are divided into germ cell and gonadal stromal (nongerm cell) tumors. Many histological and biological studies have further confirmed the distinct nature of prepubertal and postpubertal testicular tumors. These differences have led to various management strategies for prepubertal and postpubertal tumors. Because overall about 75% of prepubertal testicular tumors are benign, a testis-sparing approach is becoming more common in children. Orchiectomy and observation with very selective use of chemotherapy has become the standard approach when a malignant tumor is identified. Retroperitoneal lymph node dissection and radiation therapy play very limited roles.
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Full text: Available Index: WPRIM (Western Pacific) Main subject: Prognosis / Testicular Neoplasms / Incidence / Age Distribution / Republic of Korea Type of study: Incidence study / Prognostic study Limits: Child / Humans / Male Country/Region as subject: Asia Language: English Journal: Korean Journal of Urology Year: 2014 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Prognosis / Testicular Neoplasms / Incidence / Age Distribution / Republic of Korea Type of study: Incidence study / Prognostic study Limits: Child / Humans / Male Country/Region as subject: Asia Language: English Journal: Korean Journal of Urology Year: 2014 Type: Article