Rapid-onset of severe tigecycline-induced coagulopathy in drug reaction with eosinophilia and systemic symptom syndrome
Allergy, Asthma & Respiratory Disease
;
: 74-78, 2016.
Article
in Korean
| WPRIM
| ID: wpr-219689
ABSTRACT
Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome-also known as drug-induced hypersensitivity syndrome-is an uncommon disease entity that manifests as fever, skin rash, blood cell abnormalities, lymphadenopathy, and often coagulopathy. Tigecycline is an antibiotic that is selectively used to treat complicated intra-abdominal and soft-tissue infections. Recently, a few cases of tigecycline-induced coagulopathy have been reported. Herein, we report a case of tigecycline-induced coagulopathy in a patient with DRESS syndrome. Both prothrombin time and activated partial thromboplastin time were abruptly exceeded beyond 180 seconds on day 6 of tigecycline treatment and normalized after discontinuation of tigecycline.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Partial Thromboplastin Time
/
Prothrombin Time
/
Blood Cells
/
Eosinophilia
/
Exanthema
/
Fever
/
Drug Hypersensitivity Syndrome
/
Hypersensitivity
/
Lymphatic Diseases
Limits:
Humans
Language:
Korean
Journal:
Allergy, Asthma & Respiratory Disease
Year:
2016
Type:
Article
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