Vitamin D serum levels and risk of asthma in children
Allergy, Asthma & Respiratory Disease
;
: 44-48, 2016.
Article
in Korean
| WPRIM
| ID: wpr-219695
ABSTRACT
PURPOSE:
The role of vitamin D in traditional atopic disorders (i.e., asthma, allergic rhinitis, and atopic dermatitis) is still uncertain. We have analyzed the association between serum 25-hydroxyvitamin D3 (25(OH)-D3) levels and asthma in children.METHODS:
A total of 133 children were enrolled between April 2008 and December of 2008. Children were divided into 3 groups the asthma group (n=80), bronchiolitis group (n=50), and normal group (n=35). Serum samples were collected and checked for 25(OH)-D3 levels. From the blood samples, we measured eosinophil counts, total IgE, specific IgE (Dermatophagoides pteronyssinus, Dermatophagoides farinae, milk, egg, cat, dog, cockroach) (Uni-CAP FEIA system).RESULTS:
The mean age of the patients was 4.6 years. The mean 25(OH)-D3 levels of the asthma, bronchiolitis, and normal groups were 17.2+/-8.9, 22.5+/-9.3, and 27.8+/-10.2 ng/mL, respectively (P<0.01). There was no association between allergens and vitamin D levels. Mean 25(OH)-D3 levels were lower at acute state of asthma than at stable state.CONCLUSION:
The mean level of 25(OH)-D3 was associated with asthma and acute state of asthma. Further experimental and clinical studies are needed to establish a definite link between vitamin D levels and asthma.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Ovum
/
Asthma
/
Vitamin D
/
Vitamins
/
Calcifediol
/
Immunoglobulin E
/
Bronchiolitis
/
Allergens
/
Rhinitis
/
Dermatophagoides pteronyssinus
Type of study:
Etiology study
Limits:
Animals
/
Humans
Language:
Korean
Journal:
Allergy, Asthma & Respiratory Disease
Year:
2016
Type:
Article
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