The relationship between the presence, severity and pattern of acute placental inflammation and amniotic fluid interleukin-8 in preterm labor / 대한산부인과학회잡지
Korean Journal of Obstetrics and Gynecology
;
: 2669-2674, 1999.
Article
in Korean
| WPRIM
| ID: wpr-219697
ABSTRACT
OBJECTIVE:
To evaluate the relationship between amniotic fluid interleukin-8 and the presence, severity and pattern of acute inflammatory lesions in the placenta delivered after preterm labor with intact membranes.METHODS:
The relationship between placental histologic finding and amniotic fluid interleukin-8 was examined in 46 consecutive patients who were admitted with the diagnosis of preterm labor with intact membranes and who delivered singleton gestations within 5 days.RESULTS:
The prevalence of acute histologic chorioamnionitis was 63.0%(29/46) and that of positive amniotic fluid culture was 17.4%(8/46). The most frequent site of histologic inflammation was chorion-decidua(56.5%, 26/46). The median amniotic fluid interleukin-8 increased significantly according to the presence and higher severity of inflammation in each type of placental section (p or = 4) increased significantly in the order of non-marginating, marginating, and mixed (p<0.05 for each).CONCLUSION:
Both the presence and greater severity of acute histologic chorioamnionitis are associated with an elevated amniotic fluid interleukin-8. A marginating and mixed pattern of inflammation are associated with a higher amniotic fluid interleukin-8. Amniotic fluid interleukin-8 is a reliable prenatal marker of histologic chorioamnionitis.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Placenta
/
Prevalence
/
Chorioamnionitis
/
Interleukin-8
/
Diagnosis
/
Amniotic Fluid
/
Inflammation
/
Obstetric Labor, Premature
/
Membranes
Type of study:
Diagnostic study
/
Prevalence study
Limits:
Female
/
Humans
/
Pregnancy
Language:
Korean
Journal:
Korean Journal of Obstetrics and Gynecology
Year:
1999
Type:
Article
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