Efficacy of Immunohistochemical Staining in Differentiating a Squamous Cell Carcinoma in Poorly Differentiated Rectal Cancer: Two Case Reports
Annals of Coloproctology
;
: 150-155, 2016.
Article
in English
| WPRIM
| ID: wpr-221579
ABSTRACT
A rectal carcinoma, including primary an adenosquamous and a squamous cell carcinoma (SCC), is a very rare disease, accounting for 0.025% to 0.20% of all large-bowel malignant tumors. Because SCCs have a higher mortality than adenosquamous carcinomas, determining whether the primary rectal cancer exhibits an adenomatous component or a squamous component is important. While differentiating between these 2 components, especially in poorly differentiated rectal cancer, is difficult, specific immunohistochemical stains enable accurate diagnoses. Here, we report the use of immunohistochemical stains to distinguish between the adenomatous and the squamous components in 2 patients with low rectal cancer, a 58-year-old man and a 73-year-old woman, who were initially diagnosed using the histopathologic results for a poorly differentiated carcinoma. These data suggest that using these immunohistochemical stains will help to accurately diagnose the type of rectal cancer, especially for poorly differentiated carcinomas, and will provide important information to determine the proper treatment for the patient.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Rectal Neoplasms
/
Immunohistochemistry
/
Carcinoma, Squamous Cell
/
Mortality
/
Carcinoma, Adenosquamous
/
Rare Diseases
/
Diagnosis
/
Coloring Agents
/
Epithelial Cells
Type of study:
Diagnostic study
/
Prognostic study
Limits:
Aged
/
Female
/
Humans
Language:
English
Journal:
Annals of Coloproctology
Year:
2016
Type:
Article
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