Clinical and magnetic resonance imaging features of compressive cervical myelopathy with traumatic intervertebral disc herniation in cynomolgus macaque (Macaca fascicularis) / 한국실험동물학회지
Laboratory Animal Research
;
: 267-271, 2016.
Article
in English
| WPRIM
| ID: wpr-221829
ABSTRACT
Intervertebral disc herniation (IVDH) with nucleus pulposus extrusion, traumatic or not, is a devastating clinical condition accompanied by neurological problems. Here we report a cynomolgus macaque suffering from acute and progressive neurological dysfunction by a blunt trauma due to neck collar, an animal handling device. Tetraplegia, urinary incontinence, decreased proprioception, and imperception of pain were shown on physical and neurological examinations. MRI sagittal T2 weighted sequences revealed an extensive protrusion of disc material between C2 and C3 cervical vertebra, and this protrusion resulted in central stenosis of the spinal cord. Histopathologic findings showed a large number of inflammatory cells infiltrated at sites of spinal cord injury (SCI). This case is the first report of compressive cervical SCI caused by IVDH associated with blunt trauma.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Proprioception
/
Quadriplegia
/
Spinal Cord
/
Spinal Cord Diseases
/
Spinal Cord Injuries
/
Spine
/
Urinary Incontinence
/
Magnetic Resonance Imaging
/
Constriction, Pathologic
/
Intervertebral Disc
Limits:
Animals
Language:
English
Journal:
Laboratory Animal Research
Year:
2016
Type:
Article
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